Serum neurofilament light chain as a potential biomarker in restless legs syndrome: a cross-sectional study.

Objective: Neurofilament light chain (NfL) has emerged as a promising biomarker for several neurological diseases. Therefore, we investigated its serum levels and their association with disease characteristics, including duration, severity, and medication use in patients with restless legs syndrome (RLS).

Method: This cross-sectional prospective study included 71 RLS patients and 70 healthy controls.

Validity and reliability of the Turkish version of the Ottawa sitting scale in patients with multiple Sclerosis.

Purpose: This study aimed to examine the validity and reliability of the Turkish version of the Ottawa Sitting Scale (OSS-TR) in patients with multiple sclerosis (MS).

Methods: The study included 52 patients aged 29-45 who were diagnosed with MS based on McDonald criteria. To establish construct validity, structural (with confirmatory factor analysis, CFA) and convergent validity were examined.

Investigation of the validity, reliability and psychometric properties of the Turkish version of the Ottawa sitting scale in patients with Parkinson's disease.

The Ottawa Sitting Scale is a tool for the multidimensional assessment of sitting balance. This study aimed to investigate the validity, reliability, and psychometric properties of the Turkish version of the Ottawa Sitting Scale (OSS-TR) in Turkish-speaking patients with Parkinson's disease (PD). The study included 56 patients diagnosed with PD based on the UK Brain Bank Criteria.

Tracing the transmission of carbapenem-resistant Enterobacterales at the patient: ward environmental nexus.

Introduction: Colonisation and infection with Carbapenem-resistant Enterobacterales (CRE) in healthcare settings poses significant risks, especially for vulnerable patients. Genomic analysis can be used to trace transmission routes, supporting antimicrobial stewardship and informing infection control strategies. Here we used genomic analysis to track the movement and transmission of CREs within clinical and environmental samples.

Assessing Environmental and Economic Sustainability: Valorizing Grape Stems for Animal Feed Production.

This study evaluated an innovative strategy for valorizing grape stems (GS) from the winery industry as an animal feed ingredient from both environmental life-cycle and economic perspectives. Two processes for GS-based feed ingredient production were compared: one using hydrolyzed GS and the other using nonhydrolyzed GS, alongside the conventional animal feed production process. Using primary pilot-scale data for GS-based feed ingredient production and secondary data for animal feed production, life-cycle assessments, and economic analyses were conducted.

Is screening of patients for Pseudomonas aeruginosa groin/rectal carriage useful in identifying those at risk of bacteraemia in haematology and other high-risk clinical settings?

Background: Pseudomonas aeruginosa is a leading cause of healthcare-associated infections in patients exposed to hospital waters. A rising incidence of P. aeruginosa bacteraemia at our tertiary teaching hospital prompted investigation.

Intersubjectivity as an analytical concept to study human-animal interaction in historical context: street dogs in Late Ottoman period.

Human knowledge pertaining to human-animal interaction is constructed by the human author, albeit the presence of animal subjects. Such a human lens is pronounced when studying human-animal interactions across history, whose nonhuman animal subjects are not only absent, and therefore eliminating the possibility of conducting empirical studies , but also their experiences are filtered by the interpretative lens of human authors of extant historical accounts as well as contemporary human analysts who interpret these accounts. This article draws upon such epistemological limitations of understanding nonhuman animal presence in historical accounts and offers human-animal intersubjectivity as an analytical concept, involving generative iterability and indistinctive boundaries that emphasise intersubjective openness and relationality, to trace and disclose the continuity of human-animal co-existence.

Treosulfan is a safe and effective alternative to busulfan for conditioning in adult allogeneic HSCT patients: Data from a single center.

Introduction: Type of conditioning regimen impacts the outcome of patients who undergo allogeneic HSCT since graft versus host disease (GVHD), infections, regimen related toxicities (RRT) are important causes of post-transplant mortality. Despite the RRT profile of busulfan, it is frequently used worldwide. Treosulfan has advantages in terms of dose of administration, lower incidence of sinusoidal obstruction syndrome and lower neurotoxicity.

Carpal tunnel syndrome prediction with machine learning algorithms using anthropometric and strength-based measurement.

Objectives: Carpal tunnel syndrome (CTS) stands as the most prevalent upper extremity entrapment neuropathy, with a multifaceted etiology encompassing various risk factors. This study aimed to investigate whether anthropometric measurements of the hand, grip strength, and pinch strength could serve as predictive indicators for CTS through machine learning techniques.

Methods: Enrollment encompassed patients exhibiting CTS symptoms (n = 56) and asymptomatic healthy controls (n = 56), with confirmation via electrophysiological assessments.

Dis/re-orienting design through norm-critical gender lenses: an educational case in Turkey.

Design, as a practice of developing solutions beyond products, and increasingly services and policies, inevitably poses an impact on gender (in)equality which remains largely unrecognized by design practitioners. This paper advocates the urgent need for adopting gender lenses in design education for sustainable cultural transformation through proper recognition of the complexity of any societal and cultural issue, power relations and inequalities, and introduces an initial attempt through a graduate-level educational design project. Throughout the project, students critically reflected on existing orientations in designing to develop norm-critical gender lenses, contained the resultant disorientation emerging from the contrast between their critical approaches and local contexts, and explored novel directions as reorientation to address four different societal and cultural issues and develop 11 design outcomes aiming at gender equality, social justice-oriented empowerment, and cultural transformation.

Investigation of Layered Structure Formation in MgB Wires Produced by the Internal Mg Coating Process under Low and High Isostatic Pressures.

Currently, MgB wires made by the powder-in-tube (PIT) method are most often used in the construction and design of superconducting devices. In this work, we investigated the impact of heat treatment under both low and high isostatic pressures on the formation of a layered structure in PIT MgB wires manufactured using the Mg coating method. The microstructure, chemical composition, and density of the obtained superconductive wires were investigated using scanning electron microscopy (SEM) with an energy-dispersive X-ray spectroscopy (EDS) analyzer and optical microscopy with Kameram CMOS software (version 2.

Validity and reliability of the Modified Four Square Step Test in individuals with ankle sprain.

Background: Postural instability and gait abnormalities are frequently observed after an ankle sprain. A modified Four Square Step Test (mFSST) was developed to assess dynamic balance during gait. The aim of this study was to evaluate the reliability and validity of the mFSST in individuals with ankle sprains.

Resource utilization in the sub-sectors of the textile industry: opportunities for sustainability.

It was aimed to determine the specific resource use and reduction potential profiles in various textile sub-sectors (cotton woven fabric dyeing-finishing, wool woven fabric dyeing-finishing, synthetic woven fabric dyeing-finishing, cotton knitted fabric, synthetic knit fabric dyeing-finishing, non-woven fabric, dyeing-finishing of knitted fabric). The main focus was to elucidate opportunities for sustainability in terms of decreasing resource utilization in the textile sector. On-site surveys and detailed data collection studies were carried out at 150 textile facilities.

Five-times sit-to-stand test following anterior cruciate ligament surgery: a cross-sectional reliability study.

Aims: Patients who have had anterior cruciate ligament reconstruction (ACL-R) should periodically have their muscle strength assessed. The five-times sit-to-stand test (FTSST) can evaluate the muscle strength and balance of the lower extremities. This study's primary purpose was to assess the validity and reliability of the FTSST in patients who have undergone ACL-R.

Correlation between breast and axillary pathologic complete response after neoadjuvant chemotherapy in breast cancer.

Aim: The aim of this study was to evaluate the correlation of the pathological response in breast tissue and the axilla of patients with breast cancer who underwent surgery following neoadjuvant chemotherapy.

Method: This retrospective cohort study included patients with T1-4, N1-3, M0 breast cancer who underwent surgery following neoadjuvant chemotherapy at Gaziosmanpasa Training and Research Hospital between 2013 and 2022. The response of the breast tissue to chemotherapy was evaluated with the Miller-Payne grading system, and the response of the axillary lymph nodes to chemotherapy was evaluated with the Pinder grading system.

Enhanced monitoring of healthcare shower water in augmented and non-augmented care wards showing persistence of despite remediation work.

in healthcare shower waters presents a high risk of infection to immune-suppressed patients; identifying the colonization-status of water outlets is essential in preventing acquisition. Testing frequencies may be insufficient to capture presence/absence of contamination in healthcare waters between sampling and remediation activities. Standardization of outlets may facilitate the management and control of .

Validity and Reliability of Turkish Version of the Munich Wrist Questionnaire in Patients With Wrist Problems.

Evidence for the validity and reliability of the Turkish version of the Munich Wrist Questionnaire (MWQ), a patient reported outcome measurement tool (PROM) was evaluated. A total of 80 patients (54.1 ± 1.

Evaluation of pollution indicators and transported sediment content in agricultural drainage waters for reuse as irrigation, Harran Plain, Turkey.

The aim of this study is to determine the variation of certain pollution indicators and the level of sediment carried within drainage channel discharge waters following irrigation of fields on the Harfran Plain during the irrigation season. In this context, water samples were taken from 27 stations in total, including 26 drainage channels and 1 irrigation water channel (reference point), for 6 months between May 2020 and October 2020, and determined parameters were measured. Areal distribution maps were prepared with the ArcGIS program in order to better visually present the pollution level across the plain with the obtained data.

Seasonal monitoring of microbial activity using conventional approaches in a full-scale urban biological wastewater treatment plant.

Activated sludge processes contain various groups of microorganisms with different metabolic properties, which are responsible for contaminants removal. Therefore, it is important to elucidate the general structure and functional properties of biomass in activated sludge processes. For this purpose, a full-scale domestic biological wastewater treatment plant in Tunceli (Turkey), Tunceli WWTP (wastewater treatment plant), was monitored to observe seasonal variations in process performance and biomass properties for a year.

Use of dual energy CT urography in evaluation of urinary stone and complex cyst.

Background: Dual-energy computed tomography scans can provide significant benefits to the urinary system. The aim of this study is to determine the limitations and benefits of using dual energy CT urography in patients with urinary system stones and cysts.

Methods: In the analysis of the images, the virtual noncontrasted images obtained from the combined nephrogenicexcretory phase and the true noncontrasted images were evaluated.

Effects of COVID-19 on brain and cerebellum: a voxel based morphometrical analysis.

Objective: COVID-19 is caused by SARS-CoV-2 virus and turned into a pandemic in a short time, affects many organs and systems, especially the nervous system. In the present study, it was aimed to determine the morphological and volumetric changes in cortical and subcortical structures in recovered COVID-19 patients.

Background: We think that COVID-19 has a long-term effect on cortical and subcortical structures.

Determination of five times-sit-to-stand test performance in patients with multiple sclerosis: validity and reliability.

Purpose/aim: Although Five Times-Sit-To-Stand test (FTSST) performance is known to be a valid and reliable method in people with chronic stroke, Parkinson's disease, and balance disorder, it has not been widely studied in patients with Multiple sclerosis (MS). The main aim of this study was to evaluate validity and reliability of the FTSST in patients with MS.

Methods: The first outcome measure of the study was the FTSST, which was conducted by two different researchers.

The effect of the Covid 19 pandemic on the number of patients treated for acute and complex acute appendicitis.

Aim: The aim of this study was to compare the increase in the number of complicated cases in patients who underwent surgery for acute appendicitis during the COVID-19 pandemic and the previous year.

Material And Methods: A retrospective examination was made of the files of patients who presented at the Emergency Department and were diagnosed with acute appendicitis and underwent surgery within 24 hours or were followed up between 11 March and 1 June 2020 during the COVID-19 pandemic, and in the same period in the previous year. The patients in the pandemic period were named the pandemic group (PG) and the patients from the previous year, the control group (CG).

Daily low dose intravesical cidofovir for the treatment of BK virus associated hemorrhagic cystitis after allogeneic stem cell transplantation.

Introduction: BK virus associated hemorrhagic cystitis(BKV-AHC) is a serious complication observed after allogeneic stem cell transplantation and the current therapeutic options are scarce with substantial renal side effects. Although the guidelines recommend intravenous cidofovir application with caution to nephrotoxicity, there are few studies which investigated intravesical administration and reported similar therapeutic results with less renal side effects.

Methods: We administered low dose, daily and consecutive (75 mg/day, for 5 days) intravesical cidofovir to 25 patients with BKV-AHC that developed after (ASCT).