Publications by authors named "U Wenzel"

Background/aims: High Monomeric Polyphenols Berries Extract (HMPBE) is a formula highly rich in polyphenols clinically proven to enhance learning and memory. It is currently used to enhances cognitive performance including accuracy, working memory and concentration.

Methods: Here, we investigated for the first time the beneficial effects of HMPBE in a mouse model of acute and chronic traumatic brain injury (TBI).

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Article Synopsis
  • ANCA-associated vasculitis is a severe autoimmune disease that can lead to kidney failure due to crescentic glomerulonephritis, and current treatments using non-specific immunosuppressive drugs may be insufficient and carry risks.
  • Researchers analyzed kidney samples from 34 patients with ANCA-GN and identified specific inflammatory T cells that contribute to the disease, leading to the discovery of ustekinumab as a promising targeted treatment.
  • In a trial, four patients with recurring ANCA-GN treated with ustekinumab and low-dose cyclophosphamide showed significant improvement in kidney function and overall health, indicating potential for this approach to be further explored in clinical settings.
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  • * Most research has focused on protecting brain cells, but it's important to look at the early stages of brain inflammation too.
  • * Some foods, like those in the Mediterranean diet, and certain plant extracts might help reduce inflammation and support brain health, offering new ways to treat these diseases.
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