Publications by authors named "U Volta"
Article Synopsis
- * There was a dramatic rise in CD diagnoses post-2000, with non-classical forms being most common, and gastrointestinal symptoms like diarrhea and bloating seen in about half of the patients.
- * The study also found high rates of associated conditions, such as osteopenia in nearly 60% of patients, and suggested an evolution in disease presentation towards more subclinical and non-classical cases over time.
Background: Ultra-short coeliac disease (USCD) is defined as villous atrophy only present in the duodenal bulb (D1) with concurrent positive coeliac serology. We present the first, multicentre, international study of patients with USCD.
Methods: Patients with USCD were identified from 10 tertiary hospitals (6 from Europe, 2 from Asia, 1 from North America and 1 from Australasia) and compared with age-matched and sex-matched patients with conventional coeliac disease.
Article Synopsis
- Celiac disease (CeD) traditionally presents with positive serology and flat villi in the duodenum, but this review focuses on two lesser-known forms: seronegative CeD and ultrashort CeD.
- Seronegative CeD is identified by flat villi and positive HLA-DQ2/DQ8 without antibodies, diagnosable through clinical improvement on a gluten-free diet, while ultrashort CeD shows flat villi specifically in the duodenal bulb but not in the distal duodenum along with positive serology.
- Current research on the prevalence and characteristics of these two phenotypes is limited, but new diagnostic methods like intestinal transglutaminase 2 assessment and flow cyt
Article Synopsis
- There has been an increase in awareness about gluten-related disorders, such as celiac disease, leading to widespread misinformation about gluten-free diets (GFD) among the general public.
- While a GFD is necessary for those with celiac disease, its effects on individuals with non-celiac gluten/wheat sensitivity and other autoimmune disorders remain unclear and often lack strong evidence.
- The review focuses on how societal pressures on nutrition and body weight influence women's adherence to a GFD, highlighting its potential impact on women's health.
The role of serology in the diagnosis of coeliac disease.
Gastroenterol Hepatol Bed Bench
January 2023
Serology has significantly revolutionized the knowledge of celiac disease (CD), leading to the identification of unsuspected patients in at-risk CD groups, thereby increasing the number of CD diagnoses compared to the pre-screening era. Several markers for CD with a progressive diagnostic accuracy have been identified over the years, but only three of them, i.e.
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