Antiosteoporotic activity of OST-6(Osteocare), a herbomineral preparation in calcium deficient ovariectomized rats.

The preventive effect of the herbal formulation OST-6 (Osteocare) on the progress of bone loss induced by ovariectomy and concurrent calcium deficiency was studied in rats. Ovariectomy (OVX) and calcium deficiency (CD) resulted in bone loss as evident from decreased femoral weight and density. Treatment with OST-6 at a dose of 250 mg/kg body wt twice a day orally for a period of 16 weeks significantly restored the femoral weight and density.

Effect of Praval bhasma (Coral calx), a natural source of rich calcium on bone mineralization in rats.

Praval bhasma (PB; Coral calx) is a natural source of rich calcium widely used in traditional system of Indian medicine as a supplement in the treatment of variety of bone metabolic disorders associated with calcium deficiency. The present study was designed to investigate the inhibitory effects of Praval bhasma on the progress of bone loss induced by ovariectomy and concurrent calcium deficiency (CD-OVX). Twenty-four female rats were ovariectomized, 12 sham operated, divided into three groups of 12 each, fed on low calcium diet (0.

Inhibition of experimental cirrhosis in rats by HD-03.

Aim: To investigate the protective effect of HD-03 in experimental cirrhosis following chronic intoxication with thioacetamide (TAA).

Methods: The effect of HD-03 (750 mg/kg p.o.

The beneficial effect of OST-6 (OsteoCare), a herbomineral formulation, in experimental osteoporosis.

OST-6 (OsteoCare), a herbomineral formulation, was evaluated for its inhibitory effect on the progress of bone loss induced by ovariectomy in rats. Ovariectomized (Ovx) rats were administered with OST-6 at 250 and 500 mg/kg b.wt.

Bone mineralization by OST-6 (OsteoCare), a herbomineral preparation, in experimentally induced rickets in rats.

In the present study the efficacy of OST-6 (OsteoCare), a herbomineral preparation, on bone mineralization in experimental rickets has been evaluated. This was accomplished by feeding pregnant rats and subsequently their pups with vitamin D and calcium deficient (VDCD) with low phosphorus diet. The parameters such as serum and bone mineral contents (calcium and inorganic phosphorus), serum alkaline phosphatase, sex hormones and histology of bone were considered.