Photodynamic therapy of B16 pigmented melanoma with liposome-delivered Si(IV)-naphthalocyanine.

The possibility of extending photodynamic therapy to the treatment of highly pigmented neoplastic lesions was tested by using Si(IV)-naphthalocyanine (SiNc) as a tumor-localizing agent. Si(IV)-naphthalocyanine displays intense absorbance at 776 nm (epsilon = 5 x 10(5) M-1 cm-1), where melanin absorption becomes weaker. As an experimental model we selected B16 pigmented melanoma subcutaneously transplanted to C57BL mice.

Histopathology of diode and argon laser lesions in rabbit retina. A comparative study.

Argon lasers are the most frequently used laser source for retinal photocoagulation. These are expensive, bulky and low-efficiency devices. In contrast, diode semiconductor lasers have a number of characteristics that make them attractive for medical application: compact size, high electrical-to-optical efficiency, and long operating lifetime.

Tunable superradiant emission from a planar dye laser.

A new, simple scheme to tune a double-pass, superradiant dye laser is reported. A planar cell with a thickness below 100 microm filled with a highly concentrated (4-5 x 10(-)-M/liter) solution of Rhodamine 6G in ethanol is used. An unsaturated gain value of 1.