Publications by authors named "U Uusitalo"
Article Synopsis
- - This study examined how various factors, including diet and other influences like genetics and medical history, affect the levels of vitamins A, C, D, and E in children aged 6 months to 4 years, using data from nearly 1,500 participants.
- - Researchers found that most vitamins studied were associated with nutrient intake, but childhood infections had a negative impact on the levels of certain vitamins, particularly β-carotene and retinol.
- - The results indicate that factors outside of diet, such as infections and genetic traits, significantly influence how the body processes and utilizes these essential vitamins.
Background: Prospective longitudinal evidence considering the entire childhood food consumption in relation to the development of islet autoimmunity (IA or) type 1 diabetes is lacking.
Objectives: We studied the associations of consumption of various foods and their combinations with IA and type 1 diabetes risk.
Methods: Children with genetic susceptibility to type 1 diabetes born in 1996-2004 were followed from birth up to ≤6 y of age in the prospective birth cohort type 1 diabetes prediction and prevention study (n = 5674).
Purpose: The aim was to study the association between dietary intake of B vitamins in childhood and the risk of islet autoimmunity (IA) and progression to type 1 diabetes (T1D) by the age of 10 years.
Methods: We followed 8500 T1D-susceptible children born in the U.S.
Background: Outliers can influence regression model parameters and change the direction of the estimated effect, over-estimating or under-estimating the strength of the association between a response variable and an exposure of interest. Identifying visit-level outliers from longitudinal data with continuous time-dependent covariates is important when the distribution of such variable is highly skewed.
Objectives: The primary objective was to identify potential outliers at follow-up visits using interquartile range (IQR) statistic and assess their influence on estimated Cox regression parameters.
Article Synopsis
- Higher gluten intake in childhood is linked to a greater risk of celiac disease autoimmunity (CDA) and celiac disease, but other dietary patterns may also play a role.
- The study analyzed data from 6,726 genetically susceptible children, examining their diets at age 2 to see how it affects the likelihood of developing CDA and celiac disease as they grew older.
- Results showed that a diet rich in vegetable fats and milk at 9 months was protective against CDA, whereas a diet high in wheat and vegetable fats at 24 months increased the risk of both CDA and celiac disease.