Adult-onset dystonia: atypical manifestation of Segawa disease.

A 33-year-old woman developed exercise-induced limb and trunk dystonia with marked diurnal fluctuations. Treatment with levodopa improved her symptoms considerably but incompletely. Molecular genetic analysis revealed a mutation in GTP cyclohydrolase 1 (GCH1).

[Guillain-Barrè syndrome and inadequate antidiuretic hormone secretion syndrome].

Several neurologic disorders including Guillain-Barré syndrome (GBS) are associated with hyponatremia. Hyponatremia and its overly fast correction have major implications to the course of the underlying neurologic disease. We report a case of GBS complicated by hyponatremia secondary to the development of inadequate antidiuretic hormone secretion syndrome.

[Migraine with aura as early symptom of neurosyphilis].

Case: On the basis of a case report the often difficult classification of migraine with aura and exclusion of symptomatic origin is discussed. In spring 1996 a 34-years old patient started to suffer from attacks of a migraine like headache with focal aura several times a week. While clinical examination was inconspicuous the electroencephalogram showed a general slowing of background activity with intermittent rhythmic delta-activity.

[Anticonvulsive drugs in therapy of chronic pain--metaanalysis].

Anticonvulsive drugs provide good analgesic effect in the treatment of chronic neuropathic pain syndromes as well as in certain types of headache. Moreover these drugs may also be considered helpful for cases of non-neuropathic pain, especially if non-opioid analgesics are not effective. The optimal anticonvulsive drug for neuropathic pain is carbamazepine, while for headache prophylaxis valproic acid is recommended.

[Neurogenic pain after deafferentation through trauma. Little-known pain syndrome following amputation, brachial plexus injury and nerve root avulsion].

Amputations may be followed by such phenomena as phantom-limb pain, and pain and involuntary movements of the stump. The sequelae of brachial plexus injuries or cervical root avulsion--the second large group of deafferentiation lesions associated with neurogenic pain--are less varied, and most of these cases involve damage to the substantia gelatinosa of the spinal cord. The two groups of deafferentiation lesions are described on the basis of our own experience and reports in the literature.