Publications by authors named "U T Varyani"
Background: There is an enormous knowledge gap on management strategies, clinical outcomes, and follow-up after kidney transplantation (KT) in recipients that have recovered from coronavirus disease (COVID-19).
Methods: We conducted a multi-center, retrospective analysis in 23 Indian transplant centres between June 26, 2020 to December 1, 2021 on KT recipients who recovered after COVID-19 infections. We analyzed clinical and biopsy-confirmed acute rejection (AR) incidence and used cox-proportional modeling to estimate multivariate-adjusted hazard ratios (HR) for predictors of AR.
Background: There is limited current knowledge on feasibility and safety of kidney transplantation in coronavirus disease-19 (COVID-19) survivors.
Methods: We present a retrospective cohort study of 75 kidney transplants in patients who recovered from polymerase chain reaction (PCR)-confirmed COVID-19 performed across 22 transplant centers in India from July 3, 2020, to January 31, 2021. We detail demographics, clinical manifestations, immunosuppression regimen, laboratory findings, treatment, and outcomes.
A 52 year old previously healthy woman from Mumbai presented with fever and jaundice of 10 days duration. At admission, she was jaundiced with tachycardia, tachypnea, hypoxia, hypotension, conjunctival congestion and mild erythematous flush over the skin. She had very high WBC counts and CRP's with direct hyperbilirubinemia and azotemia.
View Article and Find Full Text PDFC1q Nephropathy in a Patient of Neurofibromatosis Type 1: A Rare Case Report.
Indian J Nephrol
January 2019
C1q nephropathy is a rare glomerular disease defined by the presence of characteristic mesangial dominant or codominant C1q deposition on immunofluorescence microscopy. Neurofibromatosis type 1 (NF-1) is an autosomal dominant syndrome caused by a mutation of a gene located on chromosomal segment 17q11.2.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated kidney paired donations (KPDs) as a viable method to boost living donor kidney transplants in a program where traditional methods are limited by costs and complications.
- Conducted at a single center, the research involved 77 KPD transplants, noting various reasons for KPD use including ABO incompatibility and sensitization, and highlighted an overall 25% increase in living donor transplants over one year.
- The findings showed high success rates with excellent graft and patient survival, and shorter waiting times for KPD compared to deceased donor transplants, emphasizing the importance of a well-organized KPD registry and counseling efforts.