Publications by authors named "U Srinivas"
Background: There is no objective criteria to wean CPAP in preterm neonates. We aimed to assess the accuracy of 'saturation trends' to predict successful CPAP discontinuation.
Methods: We included very preterm neonates who required CPAP.
Article Synopsis
- PLK1 inhibitors show promise in treating certain hard-to-treat cancers, but not all patients with PLK1 overexpression respond to these drugs due to the absence of reliable patient selection markers.
- Research found that cancer cells lacking the ARID1A tumor suppressor gene are particularly sensitive to PLK1 inhibition, not due to its usual role in cell cycle regulation, but linked to issues in their mitochondrial functions.
- The study reveals a novel role for PLK1 in supporting mitochondrial health, especially under stress, and proposes a method for identifying patients who may benefit from PLK1 inhibitors based on ARID1A protein levels.
Background: Diarrhea is one of the common gastrointestinal (GI) adverse events after solid organ transplantation. Diarrhea may be caused by infectious or non-infectious etiology. The infectious etiology of diarrhea varies according to the location and duration of diarrhea.
View Article and Find Full Text PDFCurcumin, the yellow pigment derived from turmeric rhizomes, exhibits antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. We have previously reported in a study that curcumin could induce differentiation in embryonal carcinoma cell (EC). EC cells are the primary constituents of teratocarcinoma tumors, and hence differentiating them to a non-proliferative cell type may be useful in anticancer therapies.
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