Publications by authors named "U Schmidt"
Background: Early diagnosis and treatment of mental illnesses is hampered by the lack of reliable markers. This study used machine learning models to uncover diagnostic and risk prediction markers for eating disorders (EDs), major depressive disorder (MDD), and alcohol use disorder (AUD).
Methods: Case-control samples (aged 18-25 years), including participants with Anorexia Nervosa (AN), Bulimia Nervosa (BN), MDD, AUD, and matched controls, were used for diagnostic classification.
Article Synopsis
- A study investigates therapists' views on a new treatment approach called MANTRa for young people with anorexia nervosa, highlighting the need for better therapies due to increasing eating disorder cases.
- Qualitative interviews with 10 therapists led to five themes concerning the strengths and flexibility of the MANTRa workbook, the importance of a supportive therapeutic process, and how well the treatment framework ensures quality.
- The study concludes that enhancements in MANTRa's content, therapist training, and offering a digital version could improve therapy effectiveness, while case formulation letters are identified as a valuable tool for building therapeutic relationships and aiding recovery.
Article Synopsis
- The study compares the effectiveness of guided self-help and 10-session cognitive behavioral therapy (CBT-T) against other psychological therapies for treating non-underweight binge/purge eating disorders in emerging adults.
- Data from 1,097 participants at 54 eating disorder services showed no significant differences in baseline symptoms across treatment types, but all treatments led to significant symptom improvements over time.
- The findings suggest that guided self-help and CBT-T are effective options and highlight the need for further research on their utilization in early intervention settings.
Article Synopsis
- This study uses multi-modal MRI to investigate neurobiological differences between anorexia nervosa (AN) and bulimia nervosa (BN), revealing structural and functional brain changes linked to these eating disorders.
- Key findings include reduced gray matter volume in specific brain regions (like the orbitofrontal cortex) and decreased cortical thickness, particularly in anorexia patients, which are associated with impulsivity and cognitive restraint regarding eating behaviors.
- The results suggest that these brain changes affect reward processing and contribute to the persistence of eating disorder symptoms, highlighting potential targets for future treatment interventions.
Objective: To investigate fractures history in women with first episode anorexia nervosa (AN) (FE-AN: ≤ 3 years duration) and those with persistent AN (P-AN: ≥ 7 years), compared to healthy controls (HC).
Method: One hundred nineteen women (FE-AN = 49, P-AN = 46 and HC = 24) completed online questionnaires on eating disorders symptoms, their menstrual and their fracture history.
Results: Average illness duration was 1.