Spectroscopic and density functional theory studies of trans-3-(trans-4-imidazolyl)acrylic acid.

The structural parameters, thermodynamic properties and vibrational frequencies of the optimised geometry of trans-3-(trans-4-imidazolyl)acrylic acid have been determined from B3LYP methods with 6-311++G(**) and cc-pVTZ basis sets. The effects of substituents (acrylyl group) on the imidazole vibrational frequencies are analysed. The vibrational frequencies of the fundamental modes of trans-3-(trans-4-imidazolyl)acrylic acid have been precisely assigned and analysed and the theoretical results are compared with the experimental vibrations.

Antioxidant and cytotoxic effect of oxidized lutein in human cervical carcinoma cells (HeLa).

This study investigated the antioxidant and cytotoxic effect of oxidized lutein using human cervical carcinoma cell lines (HeLa). Liposome contained phosphatidylcholine (20 micromol) in Tris-HCl buffer and lutein (200 micromol) was exposed to sunlight for 100 min. Photo-oxidized lutein products were characterized by LC-MS (APCI(+)) and studied for their antioxidant property and apoptosis in terms of cell viability, glutathione and malondialdehyde (MDA) levels.