Background: The aim of this study was to assess the impact of the ratio between the graft and host corneal size (RGH) on postoperative complications, such as immune reactions, re-bubbling rate and endothelial cell loss (ECL) after Descemet membrane endothelial keratoplasty (DMEK).
Patients And Methods: Retrospectively, 457 patient eyes were included which had undergone surgery between 2016 and 2019 in the Department of Ophthalmology, Saarland University Medical Center in Homburg/Saar using DMEK or triple DMEK, diagnosed as Fuchs' endothelial dystrophy (n = 431), pseudophakic bullous keratopathy (n = 9) and others (n = 17). The follow-up period extended until the end of 2020.
Background: Immune reaction (IR) after penetrating keratoplasty (PKP) is a serious complication with a high risk of graft failure. The aim of this study was to analyze and evaluate the risk factors for IR, in particular, the influence of graft size and centration.
Patients And Methods: A total of 2133 patients who underwent PKP between January 2009 and July 2019 were included in this retrospective study.
On average, the electronic technique for counting cells employing a Coulter counter produces higher, though comparable, numbers of cells than does manual counting in a Neubauer counting chamber. On the basis of cell size distribution, electronic counting permits a rough preliminary differentiation to be made. Owing to the much larger number of cells counted, an appreciably improved statistical analysis proves possible.
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