Possible severe thrombocytopenia associated with a single dose of plicamycin.

Objective: To report a case of possible severe thrombocytopenia associated with administration of a single dose of plicamycin.

Case Summary: A 73-year-old man with prostate cancer was admitted to the hospital with hypercalcemia (total serum calcium concentration 4.02 mmol/L) and a low baseline platelet count (152 x 10(9)/L).