is overexpressed in keloid keratinocytes and its inhibition alters profibrotic gene expression.

Background: Keloids are disfiguring, fibrotic scar-like lesions that are challenging to treat and commonly recur after therapy. A deeper understanding of the mechanisms driving keloid formation is necessary for the development of more effective therapies. Reduced vitamin D receptor (VDR) expression has been observed in keloids, implicating vitamin D signaling in keloid pathology.

GeSe-embedded metal-oxide double heterojunctions for facilitating self-biased and efficient NIR photodetection.

Infrared radiation detection is significantly important in communication, imaging, and sensing fields. Here, we present the integration of germanium selenide (GeSe) with a metal-oxide heterojunction to achieve efficient near-infrared (850 nm) photodetection under zero bias conditions. Nickel oxide (NiO) and silicon (Si) formed a favorable energy band alignment for the efficient separation of photogenerated charge carriers, resulting in a high figure of merits.

Management of Distal Radius Rim Fractures-Technical Pearls.

Distal radius fractures are common and vary based on their fracture pattern. Fractures distal to the watershed line are called rim fractures or marginal fractures. In addition to challenges already faced when treating distal radius fractures at other sites, rim fractures pose particular challenges in proper identification, reduction, and stabilization.

Efficient treatment of veterinary pharmaceutical industrial wastewater by catalytic ozonation process: degradation of enrofloxacin via molecular ozone reactions.

The study focused on the efficacious performance of bimetallic Fe-Zn loaded 3A zeolite in catalytic ozonation for the degradation of highly toxic veterinary antibiotic enrofloxacin in wastewater of the pharmaceutical industry. Batch experiments were conducted in a glass reactor containing a submerged pump holding catalyst pellets at suction. The submerged pump provided the agitation and recirculation across the solution for effective contact with the catalyst.