Molecular Design and Alignment for Ambipolar SCLC Mobility in Self-Assembled Columnar Discogens.

The future of next-generation electronics relies on low-cost organic semiconductors that are tailored to simultaneously provide all requisite optoelectronic properties, focusing greatly on ambipolar charge-transport and solution processability. In this regard, room-temperature discotic liquid crystals (DLCs) are potential candidates, where quasi-1D self-assembly affords a charge-transport channel along their columnar axis. This work shows a molecular design strategy by utilizing anthraquinone as the primary motif, surrounded by ester functionalized tri-alkoxy phenyl units to develop room-temperature DLCs (1.

An Innovative 3D-IDE Design and Adaptive Signal Extraction Algorithm for Efficient Ovarian Cancer Detection.

This work presents a facile, ultrasensitive, and selective chemiresistive biosensor assisted by an adaptive signal extraction algorithm (ASEA) for detecting vimentin, a potential biomarker for ovarian cancer detection. The low-cost device, fabricated on a PCB substrate through sacrificial copper etching, features a 3D-IDE design with interwoven comb-like structures mimicking the natural symmetry of a droplet. An unequal count of positive and negative concentric circle fingers ensures a uniform, higher electric field over the sensor's surface, as verified by COMSOL Multiphysics 3D simulation.

Ultra-wideband microstrip folded antenna for wireless LAN, 5G and Internet of Things applications.

This paper presents an ultra-wideband (UWB) microstrip antenna with a simple structure operating at 2.2-6 GHz bandwidth. The proposed antenna has been demonstrated for its suitability in UWB and multi-band applications, such as wireless local area network (WLAN), Wi-Fi, 5G, Internet of Things (IoT), etc.

Subdural Empyema in a 13-Year-Old Male With History of Head Trauma: A Case Report.

Subdural empyema is rare but serious intracranial infection characterized by accumulation of pus between dura mater and arachnoid layer. The spread of infection is typically originating from sinusitis, otitis media, or osteomyelitis. Early diagnosis by radiological imaging and prompt treatment, either by surgical intervention or by broad spectrum antibiotics are crucial to prevent life threatening complications.

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.

polymorphisms (G2019S/N2081D) that increase susceptibility to Parkinson's disease and Crohn's disease (CD) lead to LRRK2 kinase hyperactivity and suppress autophagy. This connection suggests that LRRK2 kinase inhibition, a therapeutic strategy being explored for Parkinson's disease, may also benefit patients with CD. Paneth cell homeostasis is tightly regulated by autophagy, and their dysfunction is a precursor to gut inflammation in CD.