Effects of botropase on clotting factors in healthy human volunteers.

Objective: To evaluate the effects of botropase on various clotting factors in human volunteers.

Materials And Methods: It was a prospective open label study conducted on human healthy volunteers. After the baseline screening, subjects fulfilling inclusion criteria were enrolled.

Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats.

Objective: Asparagus racemosus Willd has been used as diuretic in Ayurveda but has not been validated by a suitable experimental model. Hence the present study was undertaken.

Materials And Methods: The study was carried out with an aqueous extract of the roots of Asparagus racemosus utilizing three doses viz 800 mg/kg, 1600 mg/kg and 3200 mg/kg for its diuretic activity in comparison with standard drug (furosemide) and control (normal saline) rats after doing acute toxicity study.

Serum bicarbonate: can it be a marker of metformin induced acidosis in geriatrics?

Metformin is an oral antidiabetic agent, widely used in the treatment of type 2 diabetes mellitus. The serious side effect of metformin therapy is lactic acidosis. Contraindications for metformin therapy include renal insufficiency.

Epidemiology of accidents in tile factories of mangalore city in karnataka.

Background: Occupational accidents are a major point of concern in industries. The academic community should take the first step to address the long-neglected concerns of occupational safety.

Objective: To assess the prevalence and pattern of occupational accidents.