Publications by authors named "U P FISCH"
Objective: Large language models (LLMs) have recently gained attention for clinical decision-making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre-Trained Transformer-4omni (ChatGPT-4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance to the Status Epilepticus Severity Score (STESS).
Methods: This retrospective single-center cohort study was performed at the University Hospital Basel (tertiary academic medical center) from January 2005 to December 2022.
Article Synopsis
- The Swiss guidelines for driving with epilepsy require EEG findings to be compatible with fitness to drive (FTD), but they lack specific criteria, prompting a nationwide survey to assess how neurologists apply this in practice.
- In the survey, 102 neurologists reported variances in their assessment of EEG results, notably regarding normal variants and certain pathological patterns, revealing significant disagreement on evaluating FTD.
- The findings highlight the need for more standardized criteria and additional research, as many participants supported the inclusion of EEG results in FTD assessments but noted that follow-up tests like reaction-time evaluations were infrequently conducted.
Background: Differentiation of syncope from seizure is challenging and has therapeutic implications. Cardioinhibitory reflex syncope typically affects young patients where permanent pacing should be avoided whenever possible. Cardioneuroablation may obviate the need for a pacemaker in well-selected patients.
View Article and Find Full Text PDFObjective: The objective of this study was to assess the efficacy and tolerability of intranasal midazolam (in-MDZ) administration for antiseizure treatment in adults.
Methods: Embase and Medline literature databases were searched. We included randomized trials and cohort studies (excluding case series) of adult patients (≥ 18 years of age) examining in-MDZ administration for epilepsy, epileptic seizures, or status epilepticus published in English between 1985 and 2022.