Publications by authors named "U Neirich"

Article Synopsis
  • - The study investigates the classification of seizures associated with neural antibodies, questioning whether they should be labeled as "(auto)immune epilepsy" or "acute symptomatic seizures."
  • - A cohort of 39 patients showed that those with surface antibodies had a significantly higher probability of seizure-freedom and shorter times to stop using anti-seizure medications compared to those with intracellular antibodies.
  • - The findings suggest that seizures caused by surface antibodies are typically acute and not indicative of chronic epilepsy, impacting treatment approaches and social implications for affected individuals.
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Background: Anti-N-methyl d-aspartate receptor (NMDAR) encephalitis is a rare disorder characterized by seizures, neuropsychiatric symptoms, dyskinesia and autonomic instability.

Objective: Aim of the present study was to evaluate the seizure phenotypes and electroencephalogram (EEG) features in children with anti-NMDAR encephalitis.

Methods: Seizure types, electroclinical features and clinical characteristics of 17 children with anti-NMDAR encephalitis were analysed in a retrospective case series from nine centres in Europe.

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The aim of the study was to investigate whether nuclear immunopositivity for p53 is a factor of prognostic significance in astrocytomas of childhood and adolescence. Paraffin-embedded tissues of astrocytomas (10 WHO grade II, 11 WHO grade III) from 21 patients under 18 years of age, when operated for the first time, were studied immunohistochemically. We used a set of 6 different antibodies against p53, suitable for paraffin section (PAb1801, PAb240, DO-1, DO-7, BP53-12, CM-1).

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