[The pharmacokinetics of Z-2-amino-5-chlorobenzophenoneamidinohydrazone in the rat].

Model-independent and model-dependent pharmacokinetic parameters were determined from the course of total radioactivity in blood following single i.v., p.

[Biotransformation and excretion of Z-2-amino-5-chlorobenzophenoneamidinohydrazone].

After i.v., p.

[Biotransformation and pharmacokinetics of AWD 26-06, 8-chloro- 5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H-dibenzo[b,c] [1,4]diazepin-11-one hydrochloride, in the rat].

Following p.o. and i.

[Biotransformation and pharmacokinetics of AWD 26-06, 8-chloro-5,10-dihydro-5-[bis(2-hydroxyethyl)aminoacetyl]-11H-dibenzo[d, c][1,4]diazepin-11-one hydrochloride in the rat].

After p.o. administration to rats AWD 26-06 (1) is rapidly but incompletely absorbed.

[The metabolism of bonnecor].

Bonnecor metabolism in the rat urine was studied. The main metabolites of bonnecor were identified by means of chromatography-mass-spectrometry.