Publications by authors named "U Misra"
Background: Tenecteplase has been approved for acute ischemic stroke at a dose of 0.2 mg/kg by the Indian licensing authority. A registry to evaluate the safety of tenecteplase was mandated by the licensing authority.
View Article and Find Full Text PDFObjective: Brivaracetam (BRV), a third-generation anti-seizure medication (ASM) offers strong conformational receptor domain binding, faster blood brain barrier (BBB) permeability and better tolerability making it potential therapeutic option as an initial line or initial line add-on strategy for focal onset seizure (FoS). The following study was planned to further understand the role and relevance of BRV in the real world settings of India.
Method: This was a multicentric, cross-sectional, and non-interventional study conducted in patients with FoS across India.
Article Synopsis
- Tuberculous meningitis is a serious disease that can cause death or long-term problems for about half of the people it affects.
- Current treatment methods are based on how we treat lung tuberculosis, but they don't work as well for the brain.
- Researchers are calling for new global trials with better drugs to improve treatment and help patients with this dangerous infection.
Article Synopsis
- The study investigates the recovery patterns of different neurological functions in Guillain-Barré Syndrome (GBS), focusing on facial, bulbar, sensory, motor, and autonomic dysfunctions.
- It included 42 GBS patients, tracking their recovery over three months, noting that autonomic functions recovered the fastest, while normal motor function was less common within the follow-up period.
- Results showed that recovery times for bulbar and sensory functions were quicker in patients with the demyelinating form (AIDP) compared to the axonal form (AMAN), highlighting a consistent trend of recovery across both types of GBS.
Background: Elective intubation is advocated in Guillain-Barré syndrome (GBS) with bulbar palsy to prevent aspiration pneumonia and lung collapse. We evaluate the outcome of GBS patients with bulbar palsy, and also compare the risks and benefits of intubation and MV in them.
Methods: 187 GBS patients with bulbar palsy from a cohort of 547 GBS registry were analyzed.