The effect of antimicrobial agents on human intestinal flora, with particular reference to Bacteroides species.

The composition of human fecal flora, the methods for its study, and the changes in the normal colonic flora caused by orally administered lincomycins, tetracyclins and aminoglycosides are reviewed. Recent studies concerning the effect of the benzo-diazaborine derivative CG 3401 on human fecal flora, especially Bacteroides species, are reported.

[Treatment of urinary-tract infections with netilmicin (author's transl)].

Netilmicin, a half-synthetic aminoglycoside, was given to 22 patients with urinary-tract infections at a dose of 2 mg/kg body weight twice daily intramuscularly for 7--9 days. Pharmacokinetics (in ten patients), efficacy and tolerance to the drug were analysed. Mean serum peak concentrations on the first and last days of treatment, was 8.