Background: Failure of artemisinin-based combination therapy is increasingly reported in patients with Plasmodium falciparum malaria in sub-Saharan Africa. We aimed to describe the clinical and genomic characteristics of recent cases of P. falciparum malaria failing artemether-lumefantrine in Belgium.
View Article and Find Full Text PDFBackground: Information on human filariasis in international travelers is scarce. We describe the epidemiology, clinical presentation, and outcome of these infections in a reference travel clinic over the past decades.
Methods: We reviewed all cases of filariasis diagnosed at the Institute of Tropical Medicine, Antwerp, Belgium, from 1994 to 2018.
Cutaneous leishmaniasis is the most common presentation of infection by protozoan parasites of the genus Leishmania. Patients with cutaneous leishmaniasis may have one or several disfiguring skin lesions that resemble other dermatologic diseases. Old World cutaneous leishmaniasis is a major public health problem in the World Health Organization Eastern Mediterranean Region.
View Article and Find Full Text PDFBackground: Diagnosis of schistosomiasis remains elusive soon after infection. We evaluated several diagnostic methods in a cluster of travelers with simultaneous freshwater exposure in South Africa.
Methods: Eosinophil count, schistosome antibody tests, stool and urine microscopy, and serum Dra1 PCR assays were performed at weeks 4-5 (early symptomatic phase), 7-8 (praziquantel treatment), and 13-14 (after treatment).