Publications by authors named "U Maimunah"

Article Synopsis
  • COVID-19 can cause severe respiratory issues and may also affect liver function, but the link between the severity of the disease and liver abnormalities isn't fully understood.
  • A study analyzed 339 adult COVID-19 patients, finding that those with severe cases had significantly higher levels of liver enzymes and acute liver injury compared to non-severe cases, and lower albumin levels.
  • The research suggested that factors like HIV infection, elevated hemoglobin, and low albumin might increase the risk of liver issues in severe COVID-19 patients.
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Article Synopsis
  • Lipid accumulation product (LAP) is identified as a new predictor for central lipid accumulation linked to metabolic syndrome (MetS) and various cardiovascular diseases in both men and women.
  • A comprehensive review of 43 studies with over 200,000 participants demonstrated that LAP levels were significantly higher in individuals with MetS, showing promising diagnostic accuracy compared to traditional indicators like BMI and waist circumference.
  • With high sensitivity (85% for men, 83% for women) and specificity (81% for men, 80% for women), LAP emerges as a simple and effective screening tool for identifying MetS in adults.
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  • The interaction between the heart and liver is crucial, as conditions like constrictive pericarditis can lead to liver issues, impacting patient outcomes significantly during surgery.
  • An Indonesian man, aged 50, presented with shortness of breath and had a medical history of constrictive pericarditis, liver congestion, and abnormal lab results, culminating in a successful pericardiectomy.
  • Post-surgery, the patient showed significant improvement in health and activity levels, highlighting the importance of CTP and MELD scores in predicting recovery outcomes in cardiac patients with liver conditions.*
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Excessive release of interleukin-6 (IL-6) during the progression of coronavirus disease 2019 (COVID-19) induces cytokine storms, resulting in multi-organ damages including liver injury, similar in nature with mechanism of viral hepatitis. Systemic IL-6 has been associated with the incidence of liver injury among COVID-19 patients; however, studies on IL-6 expression in the liver tissue are completely lacking. The aim of this study was to measure the IL-6 expression in the liver tissues and to determine its correlation with the degree of liver injury in fatal COVID-19 patients.

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Article Synopsis
  • - Hepatic hydrothorax is a type of pleural effusion (≥500 mL) that occurs in patients with liver conditions like cirrhosis and portal hypertension, often associated with ascites but can be present without it in some cases.
  • - Symptoms commonly include shortness of breath, cough, nausea, and chest pain, with diagnosis confirmed through clinical signs, imaging, and thoracocentesis to rule out other potential causes.
  • - Treatment involves managing fluid production and drainage, potentially using techniques like pleurodesis or liver transplantation, as the condition can lead to serious complications like spontaneous bacterial empyema, which significantly increases the risk of morbidity and mortality.
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