Publications by authors named "U M Mogensen"
Article Synopsis
- The study aimed to assess the long-term incidence of ventricular arrhythmias (VAs) in individuals with selected autoimmune diseases (AIDs) compared to a matched control group.
- Researchers analyzed data from 186,733 patients with AIDs and found that they had a higher overall rate of VAs (an increase of 39%) compared to 746,932 matched individuals without AIDs.
- Among AIDs, systemic sclerosis showed the highest risk for VAs, and the increased risk was particularly notable in patients without pre-existing heart conditions.
Background: Conventional time-to-first-event analyses cannot incorporate recurrent hospitalizations and patient well-being in a single outcome.
Objectives: To overcome this limitation, we tested an integrated measure that includes days lost from death and hospitalization, and additional days of full health lost through diminished well-being.
Methods: The effect of dapagliflozin on this integrated measure was assessed in the DAPA-HF (Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure) trial, which examined the efficacy of dapagliflozin, compared with placebo, in patients with NYHA functional class II to IV heart failure and a left ventricular ejection fraction ≤40%.
Article Synopsis
- The study investigated the incidence of thyroid dysfunction in patients starting amiodarone treatment, particularly focusing on those with and without heart failure (HF).
- Approximately 5% of patients developed thyroid issues within the first year, with a slightly higher occurrence in those with HF.
- A clear dose-response relationship was found, indicating that higher cumulative doses of amiodarone increased the risk of thyroid dysfunction over the next five years.
A previous study has found an association between chronic inflammatory disorders e.g. psoriasis, rheumatoid arthritis, and inflammatory bowel disease and increased vascular stiffness(1).
View Article and Find Full Text PDFDirect and indirect costs of heart failure in relation to diabetes status - A nationwide study.
Nutr Metab Cardiovasc Dis
August 2022
Background And Aim: Heart failure (HF) and diabetes mellitus (DM) are burdensome chronic diseases with high lifetime risks and numerous studies indicate associations between HF and DM. The objective of this study was to investigate the direct and indirect costs of HF patients with and without DM.
Methods And Results: Patients with a first-time diagnosis of HF from 1998 to 2016 were identified through nationwide Danish registries and stratified according to DM status into HF with or without DM.