Alcohol intoxication in hospitalized young teenagers.

The scientific literature concerning alcohol intoxication is enormous. However, less is known of alcohol-induced disturbances in children and adolescents and most of those reports concern cases of hypoglycemia in children under five years of age. We studied the clinical status and chemistry, especially acid-base balance, in 36 young teenagers treated at hospital for alcohol intoxication.

Cumulative 10-year risk of symptomatic duodenal and gastric ulcer in patients with or without chronic gastritis. A clinical follow-up study of 454 outpatients.

The cumulative rate of symptomatic peptic ulcer (PU) was examined in a 10-year clinical follow-up study of 454 consecutive outpatients who had undergone diagnostic gastroscopy, from whom routine biopsy specimens were taken from the antral and corpus mucosa, and who were found to be ulcer-free before and at the time of this initial gastroscopy. During the follow-up period 34 (11%) of 321 patients who showed gastritis in the biopsy specimens at the initial gastroscopy had contracted symptomatic PU (18, 5, 7, and 4 cases of duodenal, pyloric, antral, and angular or corpus ulcer, respectively), which was verified by endoscopy. Only 1 (0.

The effect of glucocorticoids, beta-2-adrenoceptor agonists, theophylline and propranolol on the rate of ethanol elimination and blood acetate concentration in humans.

The effects of a single dose and of prolonged administration of glucocorticoids and of a single dose of salbutamol, theophylline or propranolol on the rate of ethanol elimination and blood acetate concentration were examined in healthy male students. Mean ethanol elimination rate and mean blood acetate concentration were increased significantly after acute intake of glucocorticoids. After chronic administration of glucocorticoids, the rate of ethanol elimination was significantly increased, whereas blood acetate concentration showed a tendency to increase, but did not reach statistical significance.

Increased serum acetate as a marker of problem drinking among drunken drivers.

727 consecutive drunken drivers were studied for laboratory markers of excessive alcohol consumption. Serum gamma-glutamyltransferase and alanine aminotransferase showed no differences and aspartate aminotransferase and blood alcohol concentration only small differences between groups of first and repeating drunk driving offenders. The best laboratory test to differentiate the repeating offenders with probably more serious alcohol problems from the first offenders was in our material serum acetate, the mean serum acetate level of the repeating offenders being highly significantly (P less than 0.