Detection of U wave activity in healthy volunteers by high-resolution magnetocardiography.

Introduction: The purpose of our study was to prove the existence of the U wave using magnetocardiograms (MCGs).

Methods: The 31-channel MCGs of 25 healthy volunteers were recorded. The onset of the U wave was defined by newly developed spatial correlation analysis; and the end, by different approaches.

Magnetocardiography based spatiotemporal correlation analysis is superior to conventional ECG analysis for identifying myocardial injury.

Electrocardiogram (ECG) particular from tiny, non Q-wave myocardial infarction may lack striking infarct pattern. Spatiotemporal correlation analysis (SCA) of multichannel magnetocardiogram (MCG) is a high-resolution "magnifying glass" to analyze homogeneity of repolarization. SCA involves full 4D spatiotemporal information to identify abnormalities as empirically done by eye in conventional ECG-but on an advanced level of analysis.

Comparison of current density viability imaging at rest with FDG-PET in patients after myocardial infarction.

The assessment of myocardial viability is a major diagnostic challenge in patients with coronary artery disease (CAD) after myocardial infarction. Novel threedimensional current density (CD) imaging algorithms use high-resolution magnetic field mapping to determine the electrical activity of myocardial segments at rest. We, for the first time, compared CD activity obtained with several algorithms to 18-F-fluoro-deoxyglucose positron emission tomography (FDG-PET) in evaluation of myocardial viability.

Peripheral arterial disease alters heart rate variability in cardiovascular patients.

Background: Autonomic regulation analysis is useful in risk stratification of ventricular tachycardia and sudden cardiac death in chronic heart failure (CHF). Heart rate variability (HRV) reflects the condition of autonomic regulation. For analyzing the autonomic control the whole cardiovascular system has to be considered.

Spatiotemporal correlation analyses: a new procedure for standardisation of DC magnetocardiograms.

There is a lack of standard methods for the analysis of magnetocardiograms (MCGs). MCG signals have a shape similar to the ECG (P wave, QRS complex, T wave). High-quality multichannel recordings can indicate even slight disturbances of de- and repolarisation.