3-Sulfopropyl acrylate potassium-based polyelectrolyte hydrogels: sterilizable synthetic material for biomedical application.

Hydrogels are extensively used in the biomedical field due to their highly valued properties, biocompatibility and antimicrobial activity and resistance to rheological stress. However, determining an efficient sterilization protocol that does not compromise the functional properties of hydrogels is one of the challenges researchers face when developing a material for a medical application. In this work, conventional sterilization methods (steam-, radiation- and gas sterilization) were investigated regarding the influence on the degree of swelling, mechanical performance and chemical effects on the poly 3-sulfopropyl acrylate potassium (pAESO) hydrogel, which is a promising representative for biomedical engineering applications.

Correction: 3D printed and stimulus responsive drug delivery systems based on synthetic polyelectrolyte hydrogels manufactured digital light processing.

Correction for '3D printed and stimulus responsive drug delivery systems based on synthetic polyelectrolyte hydrogels manufactured digital light processing' by Sonja Vaupel , 2023, DOI: https://doi.org/10.1039/d3tb00285c.

3D printed and stimulus responsive drug delivery systems based on synthetic polyelectrolyte hydrogels manufactured digital light processing.

Hydrogels are three-dimensional hydrophilic polymeric networks absorbing up to and even more than 90 wt% of water. These superabsorbent polymers retain their shape during the swelling process while enlarging their volume and mass. In addition to their swelling behavior, hydrogels can possess other interesting properties, such as biocompatibility, good rheological behavior, or even antimicrobial activity.

Swelling and Mechanical Characterization of Polyelectrolyte Hydrogels as Potential Synthetic Cartilage Substitute Materials.

Hydrogels have become an increasingly interesting topic in numerous fields of application. In addition to their use as immobilization matrixes in (bio)catalysis, they are widely used in the medical sector, e.g.

B(CF)-Catalyzed transfer hydrogenation of esters and organic carbonates towards alcohols with ammonia borane.

Herein, we report an efficient metal-free system for the transfer hydrogenation of esters and carbonates by-passing the otherwise ubiquitous formation of transesterification side-products. The Lewis acid B(CF) is used as catalyst and ammonia borane as hydrogen donor. This methodology shows broad substrate scope and functional group tolerance in excellent yields at very mild conditions.