Publications by authors named "U Kottler"
Purpose: This paper describes the study design, methodology, cohort profile and self-reported diseases in the ophthalmological branch of the Gutenberg Health Study (GHS).
Methods: The GHS is an ongoing, prospective, interdisciplinary, single-center, population-based cohort study in Germany. The main goals of the ophthalmological section are to assess the prevalence and incidence of ocular diseases and to explore risk factors, genetic determinants and associations with systemic diseases and conditions.
Prevalence of age-related macular degeneration in a large European cohort: results from the population-based Gutenberg Health Study.
Graefes Arch Clin Exp Ophthalmol
September 2014
Background: The aim of this study was to describe the sex- and age-specific prevalence of age-related macular degeneration (AMD) and its correlation with urban or rural residence in a large and relatively young European cohort.
Methods: We evaluated fundus photographs from participants in the Gutenberg Health Study (GHS), a population-based, prospective, observational, single-centre study in the Rhineland-Palatine region in midwestern Germany. The participants were 35-74 years of age at enrolment.
Purpose: The aim of this study was to evaluate the correlations between general anthropometric features and cardiovascular parameters and central corneal thickness (CCT) in an adult European cohort.
Methods: Analysis was based on a Gutenberg Health Study cohort that included 5000 subjects (2540 male, 2460 female), aged 35 to 74 years at enrollment. The participants underwent a standardized protocol with a comprehensive questionnaire; ophthalmic examination (slit-lamp biomicroscopy; autorefractometry; noncontact tonometry; fundus photography; CCT measurements (optical pachymetry); visual field testing; and a thorough general examination focused on cardiovascular parameters, psychosomatic evaluation, and laboratory tests including genetic analysis.
Objective: To study the distribution of refractive errors among adults of European descent.
Design: Population-based eye study in Germany with 15010 participants aged 35-74 years.
Methods: The study participants underwent a detailed ophthalmic examination according to a standardised protocol.
Article Synopsis
- The study aimed to analyze intraocular pressure (IOP) among a European adult population and its links to eye features and cardiovascular risks.
- Conducted as part of the Gutenberg Health Study, it involved 4,335 participants aged 35 to 74, who underwent extensive eye and health evaluations.
- Results showed a mean IOP lower than that in similar populations, with factors like gender, iris color, and various health indicators influencing higher IOP levels, especially in men.