Publications by authors named "U Kalawat"

Background: Over time, COVID-19 testing has significantly declined across the world. However, it is critical to monitor the virus through surveillance. In late 2020, WHO released interim guidance advising the use of the existing Global Influenza Surveillance and Response System (GISRS) for the integrated surveillance of influenza and SARS-CoV-2.

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Article Synopsis
  • - Monitoring the SARS-CoV-2 genome evolution is crucial, and this study focused on detecting variants in Andhra Pradesh, India, by sequencing the complete S-gene from 104 clinical samples using Sanger's method.
  • - The analysis revealed that the Delta variant was the most prevalent, followed by the Omicron variant, with a total of sixty-nine amino acid substitutions identified, including specific mutations associated with these variants.
  • - Phylogenetic analysis categorized the 104 samples into various clades, such as Alpha, Delta, and Omicron, highlighting the diversity of SARS-CoV-2 variants in the region and their potential impact on virulence and transmission.
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Background And Aims: A major limitation to providing oxygen therapy by high flow nasal oxygen (HFNO) delivery devices is its availability and therefore as an alternative many clinicians use a standard non rebreathing face mask (NRBM) in order to oxygenate their patients where low-flow nasal oxygen or simple facemask oxygen is not providing adequate respiratory support to achieve the target peripheral oxygen saturation (SpO). We aimed to determine the clinical effectiveness of HFNO versus NRBM in terms of improving patient outcome among patients admitted to our intensive care unit (ICU) during coronavirus disease-2019 (COVID-19) outbreak.

Methods: In this prospective open labelled study, 122 COVID-19 patients presenting with acute hypoxaemic respiratory failure (AHRF) were randomised to receive either HFNO or NRBM to achieve the target SpO.

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Purpose: Human papillomavirus (HPV) causes genital and oropharyngeal cancers worldwide. There are significant gaps exist in the data on HPV genotype prevalence in this part of the country. HPV vaccination is one of the best preventive methods available currently.

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Dengue is an arthropod-borne acute febrile illness caused by Dengue Virus (DENV), a member of . Severity of the infection ranges from mild self-limiting illness to severe life-threatening hemorrhagic fever (DHF) and dengue shock syndrome (DSS). To date, there is no specific antiviral therapy established to treat the infection.

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