Consecutive oxidative stress in CATALASE2-deficient Arabidopsis negatively regulates Glycolate Oxidase1 activity through S-nitrosylation.

Glycolate oxidase (GOX) is a crucial enzyme of photorespiration involving carbon metabolism and stress responses. It is poorly understood, however, how its activities are modulated in response to oxidative stress elicited by various environmental cues. Analysis of Arabidopsis catalase-defective mutant cat2 revealed that the GOX activities were gradually repressed during the growth, which were accompanied by decreased salicylic acid (SA)-dependent cell death, suggesting photorespiratory HO may entrain negative feedback regulation of GOX in an age-dependent manner.

The Key Targets of NO-Mediated Post-Translation Modification (PTM) Highlighting the Dynamic Metabolism of ROS and RNS in Peroxisomes.

Nitric oxide (NO) has been firmly established as a key signaling molecule in plants, playing a significant role in regulating growth, development and stress responses. Given the imperative of sustainable agriculture and the urgent need to meet the escalating global demand for food, it is imperative to safeguard crop plants from the effects of climate fluctuations. Plants respond to environmental challenges by producing redox molecules, including reactive oxygen species (ROS) and reactive nitrogen species (RNS), which regulate cellular, physiological, and molecular processes.

[Peritoneal dialysis in treatment of diffuse purulent peritonitis].

Peritoneal dialysis (PD) as a method of sanitation of the abdominal cavity was used in treatment of 221 patients (140 males and 81 females aged 17-89 years) with extended purulent peritonitis. In all patients toxic (138) of terminal (83) stage of purulent peritonitis was diagnosed. PD was carried dut in flow-fractional regimen with the use of 10-15 l of isotonic physiologic solution with the addition of antibiotics and heparin 4 times per day during 4-6 days.

[Dynamics of changes in brain metabolism in experimental peritonitis].

The condition of metabolic processes in the brain during the development of experimental peritonitis was studied in experiments on 100 unisexual pubertal rats weighting from 250 to 300 g. Blood samples were studied for the content of total protein, albumin, urea, total lipids, cholesterol, B-lipoproteins, and glucose with calculation of the arteriovenous difference (AVD) of each of these substrates. Marked phase changes in the character of metabolism of total protein, albumin, total lipids, B-lipoproteins, and glucose occur in the brain of rats with experimental peritonitis.

[The absorptive-excretory function of the liver in patients with mechanical jaundice before and after endobiliary interventions].

The authors analyze the character and degree of disturbances of the absorbing-eliminating function of the liver in 156 patients with mechanical jaundice of different etiology. In patients with mechanical jaundice the absorbing-eliminating function of the liver is disturbed at early stages of the disease and these disturbances progress at longer terms of the disease. The restoration of the absorbing-eliminating function of the liver was noted in the process of percutaneous transhepatic drainage of the bile ducts.