Engineered neural tissues serve as models for studying neurological conditions and drug screening. Besides observing the cellular physiological properties, in situ monitoring of neurochemical concentrations with cellular spatial resolution in such neural tissues can provide additional valuable insights in models of disease and drug efficacy. In this work, we demonstrate the first three-dimensional (3D) tissue cultures with embedded optical dopamine (DA) sensors.
View Article and Find Full Text PDFIntroduction: More than half a million patients suffer from minor burns in Germany per year. In 2018, almost 2000 patients needed intensive care for their burn injuries. Despite high standards of burn care, mortality remains high.
View Article and Find Full Text PDFIn this study, the morphology of an immiscible polymer blend system at various regions of interests was analyzed using different microanalytical methods with varying surface sensitivities. As a model immiscible polymer blend, a HDPE/PP (80/20 wt%) polymer film was used. The blend film was subjected to polarized light microscopy (PLM), scanning electron microscopy (SEM), atomic force microscopy (AFM), transmission electron microscopy (TEM) and time of flight secondary ion mass spectrometry (ToF-SIMS).
View Article and Find Full Text PDFErgotherapy is part of the multidisciplinary treatment concept in the field of orthopedics and trauma surgery. The occupational therapist treats patients together with doctors, nurses, physiotherapists, psychologists, social workers/pedagogues, speech therapists and other professional groups · with congenital malformations,. · with chronic diseases,.
View Article and Find Full Text PDFBackground: When a patient's statement of reduced visual acuity (VA) does not correspond to the ophthalmologic findings, the validity of the statement should be checked before intensive diagnostics are initiated, because the statement may be untrue or may overstate a factual reduction in VA. A primary question is whether the patient's statement differs from his or her true VA, and if so, by how much. Especially in examinations for medical opinion, individuals may be well informed on how to check the validity of VA statements.
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