Publications by authors named "U Hink"

Article Synopsis
  • Diabetic vasculopathy significantly contributes to coronary artery disease (CAD), primarily through oxidative stress, highlighting the need for new antioxidant treatment strategies for diabetic patients.* -
  • In a study of 20 diabetic patients and 39 non-diabetic controls undergoing heart surgery, key markers related to oxidative stress, inflammation, and lipid metabolism were analyzed, revealing increased inflammation and altered lipid profiles in diabetic patients.* -
  • The findings suggest that dyslipidemia and myocardial inflammation play critical roles in complications of diabetic CAD, with oxidative stress levels and pro-oxidative enzyme activity linked to the severity of the disease in patients.*
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Aims: During the COVID-19 pandemic, hospital admissions for cardiac care have declined. However, effects on mortality are unclear. Thus, we sought to evaluate the impact of the lockdown period in central Germany on overall and cardiovascular deaths.

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Background: In modern cardiology, anticoagulation and antiaggregation are key components of current treatment strategies. However, in patients treated with anticoagulation and antiplatelet substances, bleeding is a major risk.

Findings: In all major cardiovascular diseases, a multitude of studies have shown a positive impact of antithrombotic treatment on cardiovascular death.

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Background/objective: Prostar XL (PS) and ProGlide (PG) are common vascular closure devices (VCD) used in TAVR via transfemoral vascular approach. The impact of these VCD on vascular and bleeding complications remains unclear.

Methods: The BRAVO-3 trial randomized 802 patients undergoing transfemoral TAVR.

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Background: Obesity is one of the major cardiovascular risk factors and is associated with oxidative stress and myocardial dysfunction. We hypothesized that obesity affects cardiac function and morbidity by causing alterations in enzymatic redox patterns.

Methods: Sixty-one patients undergoing coronary artery bypass grafting (CABG) were included in the study.

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