Publications by authors named "U Hayat"
Modern breeding technologies and the development of quantitative trait locus (QTL) mapping have brought about a new era in peach breeding. This study examines the complex genetic structure that underlies the morphology of peach fruits, paying special attention to the interaction between genome editing, genomic selection, and marker-assisted selection. Breeders now have access to precise tools that enhance crop resilience, productivity, and quality, facilitated by QTL mapping, which has significantly advanced our understanding of the genetic determinants underlying essential traits such as fruit shape, size, and firmness.
View Article and Find Full Text PDFPurpose: The objective of this study was to add to the limited literature of Focal Scleral Nodule (FSN).
Methods: This study was a single-centre, retrospective, observational case series performed at Manchester Royal Eye Hospital (United Kingdom). Nineteen eyes from nineteen patients over a thirteen year period (January 2011 to January 2024) were included.
Background: Per-oral endoscopic myotomy (POEM) is an effective option for treating achalasia. Despite its high efficacy, a fraction of patients remain symptomatic after POEM, and the data on the optimal management of these patients is limited. Few studies have evaluated the effectiveness of repeat POEM after a failed POEM.
View Article and Find Full Text PDFArticle Synopsis
- Alcohol-related liver disease (ALD) is a growing public health issue, especially among people under 55, leading to an increase in alcohol-attributable deaths that are projected to rise further by 2030.
- Data from the CDC revealed a significant increase in mortality rates, particularly in the 25-34 age group, with rates climbing from 3.9 per 100,000 in 1999 to an expected 14.4 per 100,000 by 2030.
- This upward trend highlights the urgent need for public health interventions to address and reduce ALD mortality rates in younger populations.
Article Synopsis
- Dual antiplatelet therapy (DAPT) combined with proton pump inhibitors (PPI) can significantly reduce the risk of upper gastrointestinal bleeding (UGIB) in patients with acute coronary syndrome (ACS) compared to DAPT alone.
- A meta-analysis of seven randomized controlled trials involving 6708 patients showed a marked decrease in UGIB rates and all-cause mortality when PPI was added, with no negative impact on major cardiovascular events.
- Specifically, the PPI + DAPT group had a risk ratio of 0.39 for UGIB and 0.46 for mortality, indicating substantial benefits from this combination treatment.