Publications by authors named "U Harbarth"

Background/aims: To determine the sensitivity and the specificity of the GDx in the detection of (1) advanced glaucoma, (2) early glaucoma, and (3) nerve fibre bundle defects (NFBD).

Methods: Group A comprised 20 eyes with reproducible glaucomatous visual field defects confirmed by octopus perimetry, group B consisted of 10 eyes with normal visual fields but either glaucomatous NFBD or deterioration of the disc over time clearly visible upon flicker comparison, and group C included 16 eyes with glaucomatous or non-glaucomatous NFBD clearly visible on red free photographs. Forty four eyes of 22 healthy volunteers served as controls.

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Topographic analysis and measurement of the optic nerve head is important for the diagnosis and follow-up of glaucoma. To quantify structures of the optic nerve head the new technique of laser tomographic scanning was used. A laser beam was focused onto the surface of the optic nerve head and the reflected light was detected in a confocal detection unit.

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Three-dimensional topographical analysis of the optic nerve head and the parapapillary region was performed with a confocal laser tomographic scanner. Four patients with various disorders of the optic nerve head (glaucoma, optic disk pit, morning glory syndrome and a parapapillary neoplasm) were investigated as examples of application of the method in a clinical setting.

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