Publications by authors named "U H Iloeje"
Rationale: Pulmonary embolism is a rare life-threatening condition in pediatric populations. Diagnosis is often challenging in resource-constrained settings suffering chronic shortages of specialist and diagnostic services. We report the prompt recognition and challenging management of pulmonary embolism in an adolescent presenting to a private specialist hospital in a resource-constrained country.
View Article and Find Full Text PDFBackground: Neurofibromatosis type 1, -related schwannomatosis and non--related schwannomatosis (grouped under the abbreviation "NF") are rare hereditary tumor predisposition syndromes. Due to the low prevalence, variability in the range, and severity of manifestations, as well as limited treatment options, these conditions require innovative trial designs to accelerate the development of new treatments.
Methods: Within European Patient-Centric Clinical Trial Platforms (EU-PEARL), we designed 2 platform-basket trials in NF.
Article Synopsis
- Pregnancy leads to significant cardiovascular changes, particularly chronic volume overload, which can influence maternal health and is a major cause of non-obstetric maternal deaths worldwide.* -
- The study examines left and right ventricular and atrial size variations during pregnancy and postpartum in healthy women aged 18 to 40, utilizing clinical evaluations and echocardiography.* -
- Results indicate an increase in left ventricular wall thickness throughout pregnancy, with a notable decrease postpartum, while the left atrial size peaked in the third trimester.*
Article Synopsis
- Decompensated liver disease is increasingly common in medical wards and is the third leading cause of death, raising concerns about mortality rates.
- The study aimed to evaluate the effectiveness of the Model for End-Stage Liver Disease (MELD) score in predicting mortality over a 30-day period in patients with decompensated liver cirrhosis.
- Results showed that the MELD score is a reliable predictor of mortality, with a sensitivity of 72.2% and a high positive predictive value of 93.6%, indicating its strong potential for patient assessment.
Background Heart failure contributes to the global burden of cardiovascular diseases, with hypertensive heart failure affecting individuals in their productive age group and leading to high economic losses and disability-adjusted life years. The left atrium, on the other hand, contributes significantly to left ventricular filling in heart failure patients, and the left atrial function index is an excellent tool for assessing left atrial function among heart failure patients. The study aimed to evaluate some parameters of systolic and diastolic function as correlates and potential predictors of the left atrial function index among hypertensive heart failure cohorts.
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