Publications by authors named "U Giri"
Article Synopsis
- Fast radio bursts (FRBs) are intense signals from deep space that last for milliseconds and share some characteristics with pulsars, suggesting they may originate from neutron stars.
- Despite similarities, FRBs like 20221022A display different patterns in their linear polarization position angle (PA), particularly a 130° rotation that aligns with pulsar behaviors, hinting at magnetospheric origins.
- This study rules out short-period pulsars as potential sources for FRB 20221022A, supporting the idea that its unique PA evolution fits the rotating vector model commonly used for pulsars.
During the early growth phase, every individual is involved in a prolonged series of developmental processes in the maxillofacial region. Formation of cysts associated with such three-dimensional growth of the maxillofacial skeleton as well as deciduous and permanent tooth development. The origin of cystic jaw lesions may be odontogenic or non-odontogenic, developmental, or inflammatory and they are epithelial-lined or non-epithelial-lined cysts in nature.
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- Single-cell technologies allow detailed studies of how specific molecules define cell traits, but challenges like sparse data and cell differences make it tough to model biological variability.
- SCORPION is introduced as a new tool that reconstructs gene regulatory networks from single-cell RNA-sequencing data, providing reliable comparisons across different populations.
- In tests, SCORPION outperformed existing techniques and effectively identified differences in regulatory networks related to cancer, helping to reveal important factors that could affect patient survival.
Background: The National Institute of Health and Family Welfare (NIHFW) reports that India has the highest global prevalence of oral cancers. The incidence is significantly more in developing countries when compared to the developed countries. Early detection is key to increasing the survival rate of the patients.
View Article and Find Full Text PDFHistone deacetylase inhibitors (HDACi) are currently being explored for the treatment of both solid and hematological malignancies. Although originally thought to exert cytotoxic responses through tumor-intrinsic mechanisms by increasing expression of tumor suppressor genes, several studies have demonstrated that therapeutic responses depend on an intact adaptive immune system: particularly CD8 T cells. It is therefore critical to understand how HDACi directly affects T cells in order to rationally design regimens for combining with immunotherapy.
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