FUNCTIONAL AND RADIOLOGICAL OUTCOME FOLLOWING EXTENDED POSTERIOR CIRCUMFERENTIAL DECOMPRESSION IN THE TUBERCULOSIS OF DORSAL SPINE.

Spinal Tuberculosis ranks as one of the most common extrapulmonary varieties of tuberculosis. The study outlines the Extended Posterior Circumferential Decompression (EPCD) procedure for managing tuberculous spondylitis, a prevalent extrapulmonary form of tuberculosis. EPCD involves 360-degree dural decompression, anterior column debridement, and reconstruction following posterior instrumentation.

Minimally Invasive and Open Distal Chevron Osteotomy for Mild to Moderate Hallux Valgus.

Background: Minimally invasive surgical (MIS) techniques are increasingly being used in foot and ankle surgery but it is important that they are adopted only once they have been shown to be equivalent or superior to open techniques. We believe that the main advantages of MIS are found in the early postoperative period, but in order to adopt it as a technique longer-term studies are required. The aim of this study was to compare the 2-year outcomes of a third-generation MIS distal chevron osteotomy with a comparable traditional open distal chevron osteotomy for mild-moderate hallux valgus.

Electrohydrodynamic preparation of polymeric drug-carrier particles: mapping of the process.

Submicrometre size spheres prepared from biocompatible polymers are becoming increasingly popular in drug and gene delivery. This paper describes the preparation of polymeric spheres with a mean diameter of 0.4 μm with a polydispersivity index of 8%, using coaxial electrohydrodynamic atomization (CEHDA) microbubbling.

Stability of microbubbles prepared by co-axial electrohydrodynamic atomisation.

Previous studies have indicated that microbubbles prepared by co-axial electrohydrodynamic atomisation (CEHDA) are less stable than those prepared by other methods such as sonication and microfluidic techniques. The aim of this investigation was to determine the reasons for this observation and how this might be addressed in future work. Microbubbles were prepared by CEHDA using (i) a glycerol-air system, (ii) a glycerol-Tween 80-air system and (iii) a glycerol-zirconia-air system and also by simple agitation of (i) and (ii), in order to compare the effect upon the dissolution rate of microbubbles of different materials and processing methods.

Preparation of suspensions of phospholipid-coated microbubbles by coaxial electrohydrodynamic atomization.

The use of phospholipid-coated microbubbles for medical applications is gaining considerable attention. However, the preparation of lipid-coated microbubble suspensions containing the ideal size and size distribution of bubbles still represents a considerable challenge. The most commonly used preparation methods of sonication and mechanical agitation result in the generation of polydisperse microbubbles with diameters ranging from less than 1 microm to greater than 50 microm.