Publications by authors named "U Eisenmann"

Article Synopsis
  • Segmentation of lung structures in medical imaging is important for diagnosing and treating diseases like cystic fibrosis, with neural networks showing better results than traditional methods, but challenges remain with different imaging types and pathologies.
  • This study used deep learning to segment MRI scans from pediatric cystic fibrosis patients, employing the nnU-Net framework and analyzing data from 165 scans across various sequences (BLADE, VIBE, HASTE). The analysis focused on patient variability in disease severity and age.
  • Results indicated high segmentation accuracy (with Dice coefficients around 0.95-0.96) and consistent performance regardless of patient differences, although some issues with segmentation completeness were noted, particularly in the diaphragm area; the model also showed
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Background: To keep pace with the developments in the medical informatics field, the curriculum of the Heidelberg/Heilbronn Medical Informatics Master of Science program is continuously updated. In its latest revision we restructured our program to allow more flexibility to accommodate updates and include current topics and to enable students' choices.

Objectives: To present our new concepts for graduate medical informatics education, share our experiences, and provide insights into the perception of these concepts by advanced students and graduates.

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Algorithms increasing the transparence and explain ability of neural networks are gaining more popularity. Applying them to custom neural network architectures and complex medical problems remains challenging. In this work, several algorithms such as integrated gradients and grad came were used to generate additional explainable outputs for the classification of lung perfusion changes and mucus plugging in cystic fibrosis patients on MRI.

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Structured patient data play a key role in all types of clinical research. They are often collected in study databases for research purposes. In order to describe characteristics of a next-generation study database and assess the feasibility of its implementation a proof-of-concept study in a German university hospital was performed.

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Introduction: Photogrammetric surface scans provide a radiation-free option to assess and classify craniosynostosis. Due to the low prevalence of craniosynostosis and high patient restrictions, clinical data are rare. Synthetic data could support or even replace clinical data for the classification of craniosynostosis, but this has never been studied systematically.

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