[Pre-extensively and extensively drug-resistant tuberculosis, in Libreville, Gabon].

Introduction: Very few studies have been devoted to extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (TB) in Gabon.

Aim: The aim of the present study is to present the epidemiology of pre-XDR and XDR TB and the evolution over time of patients with multidrug-resistant TB.

Methods: This retrospective study covered the activities from 2019 to 2022 of the Nkembo anti-tuberculosis center.

[A rare association of Takayasu's disease and inflammatory bowel disease in Gabon].

Takayasu's disease is a vasculitis affecting large vessels, particularly the aorta and its main branches, for which the role of has been suggested as a trigger by a hypersensitivity reaction. Inflammatory bowel diseases, which in sub-Saharan Africa can be confused with parasitic diseases, can rarely be found in association with Takayasu's disease. We report an association between both diseases in the Gabonese population.

[Co-infection of malaria and COVID-19 in patients admitted to the COVID Infectious Disease Department of the Libreville University Hospital Center].

The purpose of this study was to report the cases of co-infection of malaria and COVID-19, after systematic search for plasmodium in patients treated in the COVID Infectious Disease Department (SiCOV) of the Libreville University Hospital (LUH). We conducted a prospective, observational study in the LUH SiCOV from April to July 2020. Patients of both sexes, aged over 18 years, with positive Polymerase Chain Reaction (PCR) test for SARS-CoV-2 with thick blood smear result available, were included.

Complete Blood Count Parameters, C-Reactive Protein and the Severity of Coronavirus Disease.

Background: Coronavirus disease, which initially appeared in Wuhan, China during the month of December 2019, very quickly spread and became a worldwide pandemic. The African continent was not spared. The poor health system and low socioeconomic status in some regions has raised concern on the risk of an epidemic disaster due to the rapid transmission of the virus.

[Epidemiological and evolutionary profile of tuberculosis under the influence og HIV].

Introduction: We conducted this study to understand the impact of HIV infection on the epidemiology of tuberculosis (TB) in an outpatient care center.

Patients And Methods: This is a retrospective and comparative study between subjects infected or not infected with HIV, using TB case notification data registered from October 2017 to September 2019 in the intermediate care facility (CDT) of the University Hospital of Libreville. Comparisons were made by bivariate analysis; proportions were compared using the Chi or the Fisher Exact test.