[Comparative evaluation of the transport of transit hepatotropic compounds based on mathematical modelling].

Specific features of kinetics by the hepatobiliary system 131I-BR, 131I-BS, 99mTc-pVIDA and 99mTc-NIDA have been shown. There is a definite pattern for all coefficients: a1,2 greater than a2,1; a2,1 greater than a2,3 less than a3,4. In this case the phase of absorption (a1,2) six times exceeded that of isolation of an indicator from hepatocytes (a2,3).

[Radionuclide evaluation of liver function in breast cancer based on mathematical modelling].

The paper is concerned with a clinico-diagnostic follow-up of 78 breast cancer patients: stages IIA (8), IIB (12), IIIA (39), IIIB (39), IIIC (10) and IV (9). The results of radionuclide investigations were interpreted using mathematical simulation of 131-I-rose bengal permitting separate assessment of the phases of absorption, excretion and passage via the biliary tracts. Indices of hepatocytic absorptive capacity were as follows: normal function in 41%, accelerated one in 48% and retarded in 11% of the patients.