Publications by authors named "U Caballero Silva"
Background: Digital biomarkers are increasingly used in clinical decision support for various health conditions. Speech features as digital biomarkers can offer insights into underlying physiological processes due to the complexity of speech production. This process involves respiration, phonation, articulation, and resonance, all of which rely on specific motor systems for the preparation and execution of speech.
View Article and Find Full Text PDFUnderstanding the pathogenicity of viral infections in aquatic organisms is vital due to their substantial impact on aquaculture and wild populations. This study assessed the pathogenicity of Callinectes sapidus Reovirus 2 in Callinectes danae and its effects on the metabolic, immunological and behavioural parameters. CsRV2-negative specimens were divided into CsRV2 inoculum (n = 10) and saline injection (n = 15).
View Article and Find Full Text PDFArticle Synopsis
- HIV infection leads to gastrointestinal mucosal damage, which affects microbial balance and immune response, leading to non-infectious comorbidities in people living with HIV (PLWH).
- A study measured zonulin levels in serum and intestinal tissue from HIV-infected individuals and controls, revealing higher levels of zonulin in the bloodstream of HIV patients, but lower levels in their gut tissue compared to controls.
- Elevated systemic zonulin was linked to the loss of intestinal CD4 T cells and increased gut inflammation, suggesting a relationship between zonulin and intestinal health that could be important for managing comorbidities in PLWH.
Screening for dysphagia in older people with dementia: Evidence of validity based on internal structure and reliability of the Caregiver Questionnaire - RaDID-QC.
Clinics (Sao Paulo)
August 2024
Objective: To identify internal structure validity evidence of a dysphagia screening questionnaire for caregivers of older adults with Alzheimer's disease dementia and/or vascular dementia.
Methods: The 24-question Dysphagia Screening in Older Adults with Dementia - Caregiver Questionnaire (RaDID-QC) was administered by interviewing 170 caregivers of older people with dementia, selected by convenience at the Outpatient Reference Center for Older People. Exploratory Factor Analysis (EFA) was used to assess the internal structure validity of the questionnaire, and Cronbach's alpha was used to analyze reliability.
Importance: The use of evidence-based standardized outcome measures is increasingly recognized as key to guiding clinical decision-making in mental health. Implementation of these measures into clinical practice has been hampered by lack of clarity on what to measure and how to do this in a reliable and standardized way.
Objective: To develop a core set of outcome measures for specific neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD), communication disorders, specific learning disorders, and motor disorders, that may be used across a range of geographic and cultural settings.