Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans.

Background: Apolipoprotein L1 gene () variants are risk factors for chronic kidney disease (CKD) among Black Americans. Data are sparse on the genetic epidemiology of CKD and the clinical association of variants with CKD in West Africans, a major group in the Black population.

Methods: We conducted a case-control study involving participants from Ghana and Nigeria who had CKD stages 2 through 5, biopsy-proven glomerular disease, or no kidney disease.

Prevalence of dyslipidaemia in apparently healthy professionals in Asaba, South South Nigeria.

Background: Hypercholesterolaemia is a major risk factor for coronary heart disease (CHD) especially in industrialized societies. Coronary heart disease is becoming an increasing cause of death even in the developing world.

Objective: To determine the prevalence of dyslipidaemia in apparently healthy professionals in a developing economy.

Axillary fibroadenoma mimicking lymphadenopathy.

Ectopic breast tissues are subject to the similar physiological and pathological alterations seen in breast tissues situated in their normal anatomical positions. We report a 34-year old multiparous woman who presented with a right axillary lump of about 1 year duration, for which clinical impression of axillary lymphadenopathy was made and lumpectomy carried out. Histology of excised lump revealed fibroadenoma.

The prevalence of radiological markers of renal osteodystrophy in patients with chronic renal failure in Enugu.

Objectives: To study the prevalence of renal osteodystrophy in Chronic renal failure patients in Enugu, using radiological methods.

Subjects And Methods: Ninety adult patients (56 male and 34 female) were recruited from the renal clinics of the University of Nigeria Teaching Hospital, Enugu over a period of twelve consecutive months. A structured questionnaire was administered and a physical examination carried out at the initial interview.

The hypolipidemic effects of Afzelia africana in type II diabetic patients in Nigeria.

Background: The projected rise in the world prevalence of diabetes mellitus poses new challenges in poor countries. Soluble fibre incorporation into the diet of diabetic patients has been shown to reduce the glyceamia and lipaemia of diabetes mellitus.

Design And Method: The hypolipidemic effect of soluble fibre supplementation using the seed of locally available legume tree plant--Afzelia africana was studied in 13 Nigerian patients with type 2 diabetes mellitus.