Effect of an 8-week endurance training program on markers of antioxidant capacity in women.

Aim: The effects of endurance training and of exhaustive treadmill running on low density lipoprotein (LDL) oxidation in women are not clearly established.

Methods: Twenty training and 10 control persons, all not endurance trained, aged 26+/-4 and 23+/-3 years, were recruited for 8 weeks of running training 3x/week 30 min. The susceptibility of LDL to in vitro oxidation, conjugated dienes, malondialdehyde (MDA), nitric oxide (NO) and cholesterol, lipoproteins, triglycerides, apolipoprotein (apo) A-I, apo B and lipoprotein (a) were determined before and after training, at rest and after exhaustive spiroergometric exercise.

Cardiovascular, hormone, and lipid responses to stress induced by virtual crane handling.

Objectives: The aim of the study was to test whether a mixed-mock-up-simulator (MMU-simulator) is suitable for on-the-job training by measuring stress reactions induced by handling a crane in a virtual environment in subjects not experienced in crane operation.

Materials And Methods: A MMU-simulator in a virtual environment was developed. Twenty three individuals were randomly divided into Group 1 (n = 13) and Group 2 (n = 10).

Reduction of intimal hyperplasia with Re-188-labeled stents in a rabbit model at 7 and 26 weeks: an experimental study.

The aim of this study was to analyze the feasibility of (188)Re-labeled stents to reduce neointimal formation in a rabbit atherosclerosis model and to test the long-term effects at 7 and 26 weeks. Fifty-nine male New Zealand White rabbits were fed a 0.5% cholesterol diet for 4 weeks before balloon angioplasty and insertion of Palmaz stents in the infrarenal aorta.

Intimal plaque development and oxidative stress in cholesterol-induced atherosclerosis in New Zealand rabbits.

Although oxidative stress is well known in atherogenesis, the origin, nature and kinetics of free radicals involved have not been well described till now. Here, we correlated parameters of oxidative stress with cellular components during induction and stabilization of aortic intimal lesions which were induced in rabbits by feeding a cholesterol-enriched diet for 6 weeks and a normal diet for further 68 weeks. Plasma lipids, aortic plaque size and composition (macrophages, smooth muscle cells, oxidized LDL by morphometry), as well as aortic radical production (by luminol-enhanced chemiluminescence and TEMPO-9AC fluorescence) were measured after various time points.