11C-methionine PET/CT after inconclusive 99mTc-MIBI-SPECT/CT for localisation of parathyroid adenomas in primary hyperparathyroidism.

Aim: To investigate the efficacy of PET/CT with 11C-methionine for localizing parathyroid adenomas in patients with suspected primary hyperparathyroidism and inconclusive results of cervical ultrasonography and 99mTc-MIBI-SPECT/CT.

Patients, Method: Retrospective analysis of imaging data of 18 patients and correlation with clinical outcome, in particular intraoperative findings and histopathology of excised tissue.

Results: 12 of 18 patients received surgery.

Simultaneously acquired MR/PET images compared with sequential MR/PET and PET/CT: alignment quality.

Purpose: To compare anatomic alignment between morphologic and positron emission tomography (PET) images acquired in the abdomen and pelvis by using simultaneous magnetic resonance (MR)/PET, PET/computed tomography (CT), and retrospective MR/PET fusion and to compare alignment between MR and PET in simultaneous and sequential thoracic MR/PET by using different breathing, registration, and gating protocols.

Materials And Methods: Informed consent and institutional review board approval were obtained. The misalignment in 28 abdominal patient datasets was analyzed in simultaneous MR/PET, PET/CT, and retrospective MR/PET fusion.