[Nodular lymphoid hyperplasia of the small intestinal, hypogammaglobulinemia and rheumatoid arthritis (author's transl)].

A case report is given of a patient with intestinal nodular lymphoid hyperplasia, hypoimmunoglobulinemia and seronegative rheumatoid arthritis with extensive deformation of joints, who was diagnosed and followed for 10 years clinically and by repeated endoscopic and bioptic examinations. It could be shown for the first time by temporary omission of corticosteroids that continuous therapy with corticosteroids is indispensable in this disease.

[Whipple's disease].

Whipple's disease is characterized morphologically by macrophages in the small intestine which store PAS-postive material, as well as coarsening and atrophy of the intestinal villi, with pseudocystic cavitations. Without treatment it ends fatally due to irreversible diarrhoea and cachexia. Until 1963, only 90 cases had been diagnosed, most of them at autopsy.