Publications by authors named "U Bieri"
Studies have shown that the human microbiome influences the response to systemic immunotherapy. However, only scarce data exist on the impact of the urinary microbiome on the response rates of bladder cancer (BC) to local instillation therapy. We launched the prospective SILENT-EMPIRE study in 2022 to address this question.
View Article and Find Full Text PDFPurpose: Optimal follow-up strategies following trimodal treatment for muscle invasive bladder cancer play a crucial role in detecting and managing relapse and side-effects. This article provides a comprehensive summary of the patterns and risk factors of relapse, functional outcomes, and follow-up protocols.
Methods: A systematic literature search on PubMed and review of current guidelines and institutional follow-up protocols after trimodal therapy were conducted.
Article Synopsis
- A case study was conducted on a 67-year-old man experiencing lower urinary tract symptoms (LUTS) who underwent a novel surgical procedure called transperineostomal bipolar resection of the prostate (TPR-P), which had not been previously reported in medical literature.
- The patient, with a complex medical history including Fournier's gangrene and bulbar stenosis, faced complications with catheterization but showed significant improvement following the TPR-P surgery, with reduced urinary symptoms and post-voiding residual volume.
- Despite concerns about the suitability of traditional resection techniques due to the patient's unique anatomy, TPR-P proved to be effective and safe, leading to notable enhancements in urinary function and patient satisfaction post-operation.
Objectives: The use of multiparametric magnetic resonance imaging (mpMRI) has been widely adopted in the diagnostic work-up for suspicious prostate cancer (PCa) and is recommended in most current guidelines. However, mpMRI lesions are often indeterminate and/or turn out to be false-positive on prostate biopsy. The aim of this work was to evaluate Proclarix, a biomarker test for the detection of relevant PCa, regarding its diagnostic value in all men before biopsy and in men with indeterminate lesions on mpMRI (PI-RADS 3) during work-up for PCa.
View Article and Find Full Text PDFThe transperitoneal approach (TP) and the retroperitoneal approach (RP) are two common methods for performing nephrectomy or partial nephrectomy. However, both approaches face difficulties, such as trocar placement and limited working space (RP). TP is impaired in the case of dorsal tumors and dissection of the renal artery can be challenging due to the anatomic localization dorsally to the renal vein.
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