Publications by authors named "U Bergues"
Article Synopsis
- Prokineticin 1 (PROK1) is important for endometrial receptivity and placental development, yet its potential as a noninvasive biomarker for embryo implantation is still unproven.
- The study aimed to connect PROK1 levels in follicular fluid and fertilization culture media with reproductive outcomes in IVF patients, as well as examine the expression of PROK1 and its receptors in the follicles.
- Results indicated that higher PROK1 levels were associated with successful embryo implantation, showing predictive value, while the expression of the PROK1/PROKR system was confirmed during folliculogenesis.
Article Synopsis
- - The study examined the practice of sperm freezing in patients with very low sperm counts (cryptozoospermia/severe oligozoospermia) undergoing Intracytoplasmic Sperm Injection (ICSI) over an 8-year period, aiming to assess the usage of frozen sperm. - Out of 169 patients, the majority (84) chose to freeze their sperm before ICSI while 85 did not, with an increase in sperm freezing practices observed from 29% to 74% between 2004 and 2011, yet only 5.9% of cases involved the use of frozen sperm. - The median age of patients who did not freeze their sperm was significantly higher, but there was
In spite of improvements in assisted reproductive technology (ART) during the last 30 years, the rate of pregnancy remains constrained, as only about 25 % of embryo transfer lead to successful pregnancies, even with an average of two embryos replaced. Embryo selection is currently based on the establishment of morphokinetic scores, a method that obviously exhibits limitations. Therefore, the assessment of embryo development potency by criteria of higher predictive value is mandatory in order to increase the rates of pregnancy.
View Article and Find Full Text PDFBackground: Cytogenetically detectable aberrations of the Y chromosome, such as isodicentrics, rings or translocations are sometimes associated with male non-obstructive infertility. This report presents a detailed analysis of the clinical, cytogenetic and molecular data in three patients with a re-arranged Y chromosome.
Methods: Patients A and B were azoospermic, whereas patient C was cryptozoospermic.
Patients with severe spermatogenesis impairment can now successfully father a child thanks to the use of intracytoplasmic sperm injection (ICSI). In oligozoospermic patients, many studies have reported significantly higher sperm aneuploidy rates and therefore an increased risk of transmitting a chromosomal abnormality via the injection of abnormal spermatozoa. However, the frequency of aneuploidy is highly variable between patients.
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