High blood pressure (BP) is one of the leading causes of death in Kyrgyzstan. The world's largest event in the field of increasing awareness of raised BP is the May Measurement Month (MMM) campaign. Kyrgyzstan joined MMM in 2019.
View Article and Find Full Text PDFBackground: Familial hypercholesterolemia (FH) is frequently underdiagnosed. Prevalence of the FH in Kyrgyzstan is unknown.
Aim: to investigate the prevalence of FH amongst patients in the outpatient settings of the tertiary cardiologic center in Kyrgyzstan.
Plant compounds ammonium salt of glycyrretic acid (AGA) and 18-dehydroglycyrretic acid (18-DHGA) effectively reduced the concentration of total cholesterol, triglycerides, and atherogenic lipoproteins in blood serum of rabbits with modeled cholesterol atherosclerosis. They reduced significantly the content of malonic dialdehyde and raised the activity of superoxide dismutase in the animals' organs. Due to their powerful hypolipidemic and antioxidant effect AGA and 18-DHGA significantly reduced the surface of the atherosclerotic changes of the aorta.
View Article and Find Full Text PDFThe effect of a peripheral cholinolytic methacin on the activity of lipolytic enzymes of the pancreas and small intestine was studied on intact and stress-exposed animals. The drug was shown to induce certain changes in the activity of lipolytic enzymes. The preliminary administration of methacin attenuates the shifts in the activity of the studied enzymes observed under stress action.
View Article and Find Full Text PDFThe effect of a peripheral cholinergic blocking agent on the activity of some digestive enzymes involved in protein hydrolysis was studied on albino rats under normal conditions and during stress. Metacine was administered orally. Single doses were 100, 200 and 300 mg/kg.
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