Publications by authors named "U Amann"
Purpose: Postoperative delirium (POD) is a common complication in older adult patients after surgery. A patient's preoperative anticholinergic (AC) burden is a potentially modifiable risk factor for POD. As the influence of the drug dose remains unknown, we aimed to compare three AC burden scores in relation to POD, two of which were dose-related.
View Article and Find Full Text PDFArticle Synopsis
- Drug information (DI) from hospital pharmacies is essential for safe drug therapy, but its quality needs to be better understood and assessed.
- A study analyzed responses to fictitious inquiries over five years from German hospital pharmacies to evaluate how factors like inquiry complexity, organizational structure, and quality measures affected DI quality.
- Results revealed that specialized DI centers performed better overall, particularly with complex inquiries, and recommended implementing "second look" reviews and enhanced training for pharmacists to improve quality further.
Background: Postoperative delirium (POD) is the most common complication following surgery in elderly patients. During pharmacist-led medication reconciliation (PhMR), a predictive risk score considering delirium risk-increasing drugs and other available risk factors could help to identify risk patients.
Methods: Orthopaedic and trauma surgery patients aged ≥ 18 years with PhMR were included in a retrospective observational single-centre study 03/2022-10/2022.
Purpose: Over the last decade, the use of direct oral anticoagulants (DOACs) has strongly increased. We aimed to describe and compare risk profiles including potential changes over time among persons with non-valvular atrial fibrillation initiating treatment with different DOACs or phenprocoumon (vitamin K antagonist) between 2011 and 2019 in Germany.
Patients And Methods: Using the German Pharmacoepidemiological Research Database (GePaRD; claims data of ~20% of the German population), we identified persons with a first dispensing of phenprocoumon or a DOAC and a diagnosis of non-valvular atrial fibrillation between August 2011 and December 2019.