Publications by authors named "U Alkara"
Background: In countries with low rates of deceased donor solid organ transplantations, live-donor liver transplantation is the preferred definitive treatment for children and adults with end-stage liver disease. However, it is known that a remarkable number of potential living liver donors are rejected due to ABO incompatibility, suboptimal liver mass, or anatomical features. Paired exchange liver transplantation (PELT) practice emerged to overcome these obstacles.
View Article and Find Full Text PDFArticle Synopsis
- Intraoperative blood transfusion (IOBT) during living donor liver transplantation (LDLT) is linked with negative outcomes, but many procedures may not actually require it.
- A study analyzed data from 219 adult LDLT patients, comparing those who received IOBT to those who didn't, focusing on various pre- and intraoperative factors that predict the need for transfusion.
- Results showed significant predictors for avoiding IOBT included higher preoperative hemoglobin, fibrinogen, and albumin levels, leading to a 100% one-year survival rate for the No-IOBT group versus 83% for the IOBT group.
: To evaluate the effects of the pulse index continuous cardiac output and MostCare Pressure Recording Analytical Method hemodynamic monitoring systems on short-term graft and patient outcomes during living donor liver transplantation in adult patients. : Overall, 163 adult patients who underwent living donor liver transplantation between January 2018 and March 2022 and met the study inclusion criteria were divided into two groups based on the hemodynamic monitoring systems used during surgery: the MostCare Pressure Recording Analytical Method group ( = 73) and the pulse index continuous cardiac output group ( = 90). The groups were compared with respect to preoperative clinicodemographic features (age, sex, body mass index, graft-to-recipient weight ratio, and Model for End-stage Liver Disease score), intraoperative clinical characteristics, and postoperative biochemical parameters (aspartate aminotransferase, alanine aminotransferase, total bilirubin, direct bilirubin, prothrombin time, international normalized ratio, and platelet count).
View Article and Find Full Text PDFLiving donor liver transplantation for patients with portal vein thrombosis: high-volume single center experience.
Eur Rev Med Pharmacol Sci
June 2024
Objective: End-stage liver disease is commonly associated with portal vein thrombosis (PVT). Lastly, PVT is no longer an absolute contraindication for liver transplantation, and many centers adopt portal vein thrombectomy. PVT imposes special technical difficulties during living donor liver transplantation (LDLT).
View Article and Find Full Text PDFFactors Affecting Bile Complications After Liver Transplantation: Single-Center Experience.
Sisli Etfal Hastan Tip Bul
June 2022
Objectives: In this study, we aimed to investigate the surgical technique and biochemical parameters that affect biliary complications in liver transplants from live and cadaver in our center.
Methods: In this study, 141 patients who underwent liver transplants at Istanbul Yeni Yüzyıl Universty Gaziosmanpaşa Hospital organ transplant center between January 2018 and January 2020 were included in the study. The patients were monitored for 12-24 months.